Results 91 to 100 of about 531,669 (333)

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Sinking particle flux and physical-biological oceanographic dataset during ENSO event (1997-1999) in the South China Sea

open access: yes, 2021
The file DS01_改 is a replacement of the previous file named DS01 in responses to the comments during the review ...
Li H., L., Wiesner M., G., Chen J., F.
openaire   +1 more source

Requirements on common solutions to the LSND and MiniBooNE excesses: a post-MicroBooNE study

open access: yesJournal of High Energy Physics, 2022
The strong statistical significance of an observed electron-like event excess in the MiniBooNE (MB) experiment, along with an earlier similar excess seen in the Liquid Scintillator Neutrino Detector (LSND), when interpreted in conjunction with recent ...
Waleed Abdallah, Raj Gandhi, Samiran Roy
doaj   +1 more source

Inelastic Diffraction at Heavy Ion Colliders

open access: yes, 2005
The heavy ion physics approach to global event characterization has led us to instrument the forward region in the PHENIX experiment at RHIC. In heavy ion collisions this coverage yields a measurement of the "spectator" energy and its distribution about ...
Adler   +12 more
core   +3 more sources

XENONnT analysis: Signal reconstruction, calibration, and event selection [PDF]

open access: yesPhysical Review D
The XENONnT experiment, located at the INFN Laboratori Nazionali del Gran Sasso, Italy, features a 5.9 tonne liquid xenon time projection chamber surrounded by an instrumented neutron veto, all of which is housed within a muon veto water tank. Because of
E. Aprile   +166 more
semanticscholar   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

New particle formation events observed at King Sejong Station, Antarctic Peninsula – Part 1: Physical characteristics and contribution to cloud condensation nuclei [PDF]

open access: yesAtmospheric Chemistry and Physics, 2018
Abstract. The physical characteristics of aerosol particles during a particle burst observed at King Sejong Station in Antarctic Peninsula from March 2009 to December 2016 were analyzed. This study focuses on the seasonal variation in parameters related to particle formation such as the occurrence, formation rate (FR) and growth rate (GR), condensation
J. Kim   +9 more
openaire   +4 more sources

PYTHIA 6.4 Physics and Manual [PDF]

open access: yes, 2006
The Pythia program can be used to generate high-energy-physics ''events'', i.e. sets of outgoing particles produced in the interactions between two incoming particles.
T. Sjostrand, S. Mrenna, P. Skands
semanticscholar   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

A likelihood framework for cryogenic scintillating calorimeters used in the CRESST dark matter search

open access: yesEuropean Physical Journal C: Particles and Fields
Cryogenic scintillating calorimeters are ultra- sensitive particle detectors for rare event searches, particularly for the search for dark matter and the measurement of neutrino properties.
CRESST Collaboration   +59 more
doaj   +1 more source

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