Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Limited Evidence for Probabilistic Cueing Effects on Grating-Evoked Event-Related Potentials and Orientation Decoding Performance. [PDF]
Psychophysiologyden Ouden C +3 more
europepmc +1 more source
Event-related potentials recorded during the discrimination of improbable stimuli
, 1983 Peter L. Fitzgerald, Terence W. Picton
openalex +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Three-dimensional shape from shading is modulated by top-down attention: Evidence from event-related potentials. [PDF]
IperceptionMatthews JP, Mills DL, Sapir A.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The Neurophysiological Features of Anticipation in Schizophrenia: A Cross-Sectional Study of Event-Related Potentials. [PDF]
Consort PsychiatrRabinovich E, Telesheva K.
europepmc +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Differential Effects of Self-Initiated, Externally Triggered, and Passive Movements on Action-Outcome Processing: Insights From Sensory and Motor-Preparatory Event Related Potentials. [PDF]
Eur J NeurosciOdy E, Kircher T, He Y, Straube B.
europepmc +1 more source
Quantification of Order Patterns Recurrence Plots of Event Related Potentials
, 2007 Norbert Marwan +2 more
openalex +1 more source