Results 171 to 180 of about 424,581 (304)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Statistical inference after variable selection in Cox models: a neutral simulation study. [PDF]

BMC Med Res Methodol
Schemet L, Friedrich-Welz S.
europepmc   +1 more source

Spiral Energy Bubbles as Emergent Structures in Relational Eventism

Trio Trio Lutfi
openalex   +1 more source

Community structure and composition of meiofauna over a sea-induced mouth-breaching event in St Lucia Estuary, South Africa [PDF]

, 2012
Sarah J. Bownes, Renzo Perissinotto
openalex   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Hierarchical Prototype Alignment for Video Temporal Grounding. [PDF]

Entropy (Basel)
Tian Y, Guo X, Wang J, Zhao Y, Li B.
europepmc   +1 more source

Event Structure and Causative Meaning in English and Vietnamese: A Cross Linguistic Analysis of CAUSE–BECOME Configurations

Tuyen Tran Thi Kim
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A unified framework for complex survival data: accounting for clustering, cure fractions, and competing risks. [PDF]

BMC Med Res Methodol
Wang Y, Li J, Zhou Q, Wang W.
europepmc   +1 more source

Structured Event Representation and Stock Return Predictability [PDF]

Gang Li, Dandan Qiao, Mingxuan Zheng
openalex