Results 201 to 210 of about 424,581 (304)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Single-Molecule Discrimination of Multisialylated Ganglioside Oligosaccharides Using an Engineered Nanopore. [PDF]

Research (Wash D C)
Yao G, Ren B, Zhu D, Tan J, Hou J, Ma Y, Hang Z, Xu Z, Gao Z, Li T, Xia B.   +10 more
europepmc   +1 more source

Mars Structure Service: Single-station and single-event marsquakeinversion for structure using synthetic Martian waveforms

, 2019
Drilleau, M., Khan, A., Beucler, E., Panning, M.P., Lognonné, P., Beghein, Caroline, Xu, Haotian, Menina, Sabrina, Barkaoui, Salma, Lekic, Vedran, Stahler, S. C., van Driel, M., Kenda, B., Murdoch, Naomi, Clinton, John F., Giardini, Domenico, Smrekar, Suzanne, Stutzmann, E., Schimmel, Martin   +18 more
openalex   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Interplay Between Vertical and Horizontal Schemes of Computation: From Bayesian Inference to Quantum Logic via Gluing Boolean Algebras. [PDF]

Entropy (Basel)
Gunji YP, Nakamura K, Sasai K, Tani I, Kuroki M, Chiolerio A, Adamatzky A, Khrennikov A.   +7 more
europepmc   +1 more source

Information transformation : the structures of BSE and the strategic predetermination of information events [PDF]

, 2006
Samantha Lay
openalex  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Amplified chiroptic response in a multi-helical penta-perylene structure. [PDF]

Chem Sci
Pedersen SK, Steigerwald ML, Nuckolls C, Pittelkow M.   +3 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Temporal codes and recurrent timing nets for rhythmic expectancy. [PDF]

Front Comput Neurosci
Cariani P, Baker JM.
europepmc   +1 more source