Results 221 to 230 of about 15,467,810 (252)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Frequency and Circumstances of Falls Events in People Living With Spinal and Bulbar Muscular Atrophy: A Cross-Sectional Survey. [PDF]

Physiother Res Int
Lee LE, Zampedri L, Jayaseelan D, Rinaldi C, Fratta P, Ramdharry GM.   +5 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Group-Specific Nonlinear Mixed Effects Models for Longitudinal Data With Realignment of Time. [PDF]

Stat Med
Liu Z, Gao S.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Pericoronary Adipose Tissue Radiomics-Based Prediction Models for Cardiovascular Events: A Systematic Review of Predictive Performance, Validation, and Incremental Value. [PDF]

Int J Gen Med
Shao J, Zhao H, Ding W, Gui Y, Wang W, Wang J, Wang C.   +6 more
europepmc   +1 more source

Receptor-Targeted Antiemetic Strategies in Cats: A Systematic Review and Intervention-Specific Meta-Analysis. [PDF]

Vet Med Sci
Ersöz U, Özkalipci Ç.
europepmc   +1 more source

Experiences and perceptions of lay bystanders responding to out-of-hospital cardiac arrest: A qualitative systematic review. [PDF]

Medicine (Baltimore)
Zhan S, Jiang X, Yang M, Liu M, Liu H, Li S.   +5 more
europepmc   +1 more source

Intranasal Dexmedetomidine for Paediatric Procedural Sedation in the Emergency Department: A Single-Centre Retrospective Observational Cohort Study. [PDF]

Emerg Med Australas
Whyte E, Emeto TI, Snowden F, Gangathimmaiah V.   +3 more
europepmc   +1 more source