Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Market reactions to the arrival and containment of COVID-19: An event study. [PDF]
Financ Res Lett, 2021 Heyden KJ, Heyden T.
europepmc +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Will the Volume-Based Procurement Policy Promote Pharmaceutical Firms' R&D Investment in China? An Event Study Approach. [PDF]
Int J Environ Res Public Health, 2021 Hu Y, Chen S, Qiu F, Chen P, Chen S.
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
El papel de la liquidez en el efecto de la nueva información. El caso de Latibex
El Trimestre Económico, 2010 En 1999 se creó en España el mercado Latibex destinado a la contratación en euros de valores de las principales empresas latinoamericanas. Desde su creación este mercado se ha caracterizado por tener una menor actividad negociadora y menor liquidez que ...
C. José García +2 more
doaj
Can We Compare Attributable Risk of Adverse Events with the Self-Controlled Case Series Design in Vaccine Safety Studies? A Use Case of Guillain-Barré Syndrome [PDF]
Caihua Liang +9 more
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The financial impact of COVID-19: Evidence from an event study of global hospitality firms. [PDF]
Res Int Bus Finance, 2021 Clark J, Mauck N, Pruitt SW.
europepmc +1 more source