Results 61 to 70 of about 333,150 (197)

Applying the Estimand Framework to Non‐Inferiority Trials

Pharmaceutical Statistics, Volume 23, Issue 6, Page 1156-1165, November/December 2024.
ABSTRACT Most published applications of the estimand framework have focused on superiority trials. However, non‐inferiority trials present specific challenges compared to superiority trials. The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use notes in their addendum on estimands and sensitivity ...
Helle Lynggaard, Oliver N. Keene, Tobias Mütze, Sunita Rehal   +3 more
wiley   +1 more source

Carfilzomib‐Induced Thrombotic Microangiopathy—Two Case Reports

Cancer Reports, Volume 7, Issue 10, October 2024.
ABSTRACTBackgroundThrombotic microangiopathy (TMA) is a pathological syndrome characterized by a combination of three key features: microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and organ damage, primarily affecting the kidneys. There are several drugs known to have a definite or probable causal association with TMA, and carfilzomib, a ...
Irene Attucci, Sofia Pilerci, Maria Messeri, Ludovica Pengue, Giulia Tomasino, Leonardo Caroti, Alessandro M. Vannucchi, Elisabetta Antonioli   +7 more
wiley   +1 more source

O cuidar de si como uma dimensão da cultura de segurança do paciente [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2013.A ocorrência de fatores desencadeantes de eventos adversos no cuidado de enfermagem e a sua relação com a
Gasperi, Patricia de
core  

Rastreadores para a busca ativa de eventos adversos a medicamentos em recém-nascidos

Cadernos de Saúde Pública, 2018
O objetivo foi verificar a aplicação e o desempenho dos rastreadores para a busca ativa de eventos adversos a medicamentos em recém-nascidos hospitalizados. Trata-se de um estudo de coorte prospectivo.
Sandra de Carvalho Fabretti, Sandra Cristina Brassica, Marco Antonio Cianciarullo, Nicolina Silvana Romano-Lieber   +3 more
doaj   +1 more source

A placebo‐controlled, double‐blind study evaluating the effect of orally administered polyunsaturated fatty acids on the oclacitinib dose for atopic dogs

Veterinary Dermatology, Volume 35, Issue 4, Page 408-417, August 2024.
Background – Supplementation of polyunsaturated fatty acids (PUFA) enables dose reduction of prednisolone and ciclosporin in canine atopic dermatitis (cAD). Objective – To determine if oral administration of PUFA can reduce the dose of oclacitinib for cAD. Conclusion – Oral supplementation of PUFA allowed dose reduction of oclacitinib and improved pVAS,
Laura Schäfer, Nina Thom
wiley   +1 more source

Relationship between two pathogens in an amphibian community that experienced mass mortalities

Conservation Biology, Volume 38, Issue 3, June 2024.
Abstract Because host species tend to harbor multiple parasitic species, coinfection in a host is common. The chytrid fungus Batrachochytrium dendrobatidis (Bd) and the viruses in the genus Ranavirus (Rv) are responsible for the decline of amphibians worldwide.
Barbora Thumsová, Gonzalo Alarcos, Cesar Ayres, Gonçalo M. Rosa, Jaime Bosch   +4 more
wiley   +1 more source

Los eventos adversos: ¿objetivos o consensuados? [PDF]

Acta bioethica, 2012
An adverse event is not an objective problem, since its measure or quantification does not constitute the problem as a field with explanations and statements, but the application of shared validation criteria of causal explanations by a community of observers in their experience.
openaire   +2 more sources

Reporte de eventos adversos en una unidad de cuidados intensivos de Tunja, Colombia

Revista de la Facultad de Ciencias Médicas de Córdoba, 2013
Introducción: La seguridad de paciente en áreas hospitalarias críticas ha sido tema de diversas investigaciones. En este sentido, en Colombia está creciendo la conciencia acerca de la gestión de eventos adversos.
Efraín Riveros, Paula Amado, Paula Zambrano   +2 more
doaj   +1 more source

The network structure of psychopathological and resilient responses to the pandemic: A multicountry general population study of depression and anxiety

Journal of Traumatic Stress, Volume 37, Issue 1, Page 126-140, February 2024.
Abstract Commonly identified patterns of psychological distress in response to adverse events are characterized by resilience (i.e., little to no distress), delayed (i.e., distress that increases over time), recovery (i.e., distress followed by a gradual decrease over time), and sustained (i.e., distress remaining stable over time). This study aimed to
Alba Contreras, Sarah Butter, Umberto Granziol, Anna Panzeri, Vanesa Peinado, Almudena Trucharte, Orestis Zavlis, Carmen Valiente, Carmelo Vázquez, Jamie Murphy, Marco Bertamini, Mark Shevlin, Todd K. Hartman, Giovanni Bruno, Giuseppe Mignemi, Andrea Spoto, Giulio Vidotto, Richard P. Bentall   +17 more
wiley   +1 more source

Cost minimization analysis: use of dual and triple lumen central venous cateter / Análise de custo minimização: uso do cateter venoso central de duplo e triplo lúmen

Revista de Pesquisa Cuidado é Fundamental Online, 2021
Objetivo: analisar o custo da utilização do cateter venoso central de duplo versus triplo lúmen em uma unidade de terapia intensiva. Métodos: estudo de custo-minimização, com abordagem quantitativa à luz da avaliação econômica de saúde.
Thais Cardoso da Costa, Cristiano Bertolossi Marta, Antonio Augusto de Freitas Peregrino, Ronilson Gonçalves Rocha, Andrezza Serpa Franco, Flávia Giron Camerini   +5 more
doaj   +4 more sources