Results 151 to 160 of about 6,403,842 (262)

Risks from self-medicating with psychedelic drugs. [PDF]

World Psychiatry
Black JC.
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Methods for analyzing recurrent and terminal events considering composite and competing endpoints in clinical trials: a practical overview. [PDF]

BMC Med Res Methodol
Duoerkongjiang A, Zapf A, Kirchhof P, Ozga AK.   +3 more
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A framework for developing, validating, and utilizing automated measures of order errors using the retract-and-reorder methodology. [PDF]

JAMIA Open
Spector PR, Grauer A, Kneifati-Hayek JZ, Ranard BL, Applebaum JR, Fernandes Y, Salmasian H, Southern WN, Schechter CB, Hruby G, Cooke JT, Kumaraiah D, Fertel B, Adelman JS.   +13 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Enhancing meaning in life and reducing radicalization, extremism, and violence in war and conflict-affected populations: A controlled feasibility study of the Meaning-Making App

Journal for Deradicalization
This study evaluated the feasibility of the Meaning-Making App (MMA). MMA aimed to help civilians in armed conflicts maintain a sense of meaning in life, to improve psychological well-being and reduce risks of radicalization, extremism, and violence. MMA
Joel Vos
doaj  

Warming accelerates drought-flood oscillations and stratifies socioeconomic exposure. [PDF]

PNAS Nexus
Qi W, Huang R, Cai Y, Tan Q, Ren M, Liu Y.   +5 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Inter-crystal scatter recovery of a light-sharing depth-encoding Prism-PET prototype scanner using a diffusion model. [PDF]

Med Phys
Tan W, Dosi S, Shabani Sichani S, Li Y, Wang Z, Petersen E, Zeng X, Qi J, Goldan AH.   +8 more
europepmc   +1 more source