Results 251 to 260 of about 1,940,060 (340)

Daily fluctuations in sleep duration and quality affect next-day processing speed performance in young and older adults: an intensive longitudinal everyday life study over 21 days. [PDF]

Sleep
Schwarz J, Freidle M, van Leeuwen W, Silfverling J, Åkerstedt T, Kecklund G.   +5 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Gaining More Ease in Everyday Life as a Family With a Child With Intellectual Disability Through Family-Systemic Therapeutic Conversations: An Exploratory Single-Case Study. [PDF]

J Fam Nurs
Wildhaber SP, Sgier C, Hilpertshauser M, Huber E.   +3 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Person, temporal, and contextual predictors of momentary purpose in everyday life. [PDF]

Pers Individ Dif
Sutin AR, Luchetti M, Karakose S, Stephan Y, Hajek A, Terracciano A.   +5 more
europepmc   +1 more source

The culinary act in everyday life : definition and pilot study

, 2017
Sarah Bastien, Clémentine Hugol‐Gential, Jean-Jacques Boutaud   +2 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Welfare and Everyday Life

Sociologia, 2011
Jelena Zlatar
doaj  

Help us make a better flow in everyday life - family needs in home-based pediatric palliative care: a qualitative study. [PDF]

BMC Palliat Care
Martinsen LJ, Steindal SA, Holmen H, Winger A.   +3 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source