Results 51 to 60 of about 37,437 (323)

Active DNA damage eviction by HLTF stimulates nucleotide excision repair

open access: yesMolecules and Cells, 2022
Nucleotide excision repair (NER) counteracts the onset of cancer and aging by removing helix-distorting DNA lesions via a ‘cut-and-patch’-type reaction.
Marvin van Toorn   +20 more
semanticscholar   +1 more source

Histone H3K4me1 and H3K27ac play roles in nucleosome eviction and eRNA transcription, respectively, at enhancers

open access: yesThe FASEB Journal, 2021
Histone H3K4me1 and H3K27ac are enhancer‐specific modifications and are required for enhancers to activate transcription of target genes. However, the reciprocal effects of these histone modifications on each other and their roles in enhancers are not ...
Yu-Jin Kang   +3 more
semanticscholar   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Politique de déguerpissement et processus de restructuration des territoires de Libreville [Gabon]

open access: yesL'Espace Politique, 2014
Evictions are plentiful in sub-Saharan Africa. Libreville, capital of Gabon, does not make an exception to this rule. Since the 1970s, eviction appears as a fundamental step in the restructuring process of Libreville’s space where built up areas are ...
Rano-Michel Nguema
doaj   +1 more source

The Health Impacts of Eviction: Evidence from the National Longitudinal Study of Adolescent to Adult Health

open access: yesSocial Science & Medicine (1967), 2021
Eviction represents an urgent social and economic issue in the United States, with nearly two million evictions occurring annually in the U.S. Still, the population health impacts of evictions, as well as the pathways linking eviction to health, are not ...
Morgan K. Hoke, Courtney Boen
semanticscholar   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Le parc national du Mont Péko (Côte d’Ivoire) entre dynamiques de déguerpissement, tensions sociales et logiques des acteurs : vers un risque d’explosion de violences

open access: yesÉtudes Caribéennes, 2016
The arrest in May 2013 of Amade Oueremi, the emblematic leader of mont Peko national park infiltrators, opened the way to a public policy of conservation and tourism development of this 34 000 ha protected area almost entirely colonized by cocoa farms ...
Kouamé Walter Kra
doaj   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

open access: yesAdvanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su   +4 more
wiley   +1 more source

The Evicted [PDF]

open access: yesArts, 2019
The following essay examines Anthony Hernandez’s photographic work from the early 1970s to the present. The essay addresses how Hernandez reimagines the genre of street photography in Los Angeles, countering the misconception that the genre, so dominant in the history of the medium, is nearly inexistent in California.
openaire   +3 more sources

TED1 Promotes the Assembly of SCFD3‐D14‐D53 to Reinforce Strigolactone Signaling in Rice

open access: yesAdvanced Science, EarlyView.
This study identifies TED1 as a positive regulator of strigolactones (SL) signaling in rice. The ted1 mutants display dwarfism and increased tillering with significantly reduced SLs sensitivity. Through its longer C‐terminal region, TED1 interacts with D53 and D14 to promote the assembly of SCFD3‐D14‐D53, thereby facilitating the efficient ...
Sheng Luo   +22 more
wiley   +1 more source

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