Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Evidence-Based Medicine Culture, Curriculum, and Program Outcomes: A CERA Study. [PDF]
Fam MedRowland K +6 more
europepmc +1 more source
Insights from Evidence-Based Medicine Method for Building Security Systems Against Terrorist Attacks in Hospitals. [PDF]
J Multidiscip Healthc, 2023 Chen G, Jin G.
europepmc +1 more source
The need and means for evidence-based medicine in developing countries [PDF]
, 2000 openalex +1 more source
HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4
FEBS Open Bio, EarlyView.Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang +11 more
wiley +1 more source
From Questions to Answers: Teaching Evidence-Based Medicine Question Formulation and Literature Searching Skills to First-Year Medical Students. [PDF]
MedEdPORTALMagro J +3 more
europepmc +1 more source
Breast reconstruction in the era of evidence-based medicine. [PDF]
Ann Transl Med, 2023 Manrique OJ, Escandón JM.
europepmc +1 more source
Transmission of infectious diseases through mouth-to-mouth ventilation: evidence-based or emotion-based medicine? [PDF]
, 2000 C Arend
openalex +1 more source
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
FEBS Open Bio, EarlyView.We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo +2 more
wiley +1 more source
Using Social Media to Teach About and Engage Residents in Evidence-Based Medicine. [PDF]
Fam MedCastelli G, Winters S, Taylor A, Ge Y.
europepmc +1 more source