Results 281 to 290 of about 6,549,758 (385)

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

New update of the international PCOS guideline-Focus on evidence-based medicine in the treatment of PCOS. [PDF]

Acta Obstet Gynecol Scand
Forslund M, Melin J, Piltonen T, authors of the paper.   +3 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

The Role of Cannabinoids in Advancing Cancer Treatment: Insights from Evidence-Based Medicine. [PDF]

Curr Oncol Rep
Skórzewska M, Gęca K.
europepmc   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Patient perspective: Is intensive screening of women at high risk of breast cancer evidence-based medicine or <i>déjà vu</i>? [PDF]

Womens Health (Lond)
Fairman KA.
europepmc   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines.

Wideochir Inne Tech Maloinwazyjne
Szeliga J, Jagielski M, Sobocki J, Borys M, Czuczwar M, Durczyński A, Gach T, Hogendorf P, Kawiński A, Kuśnierz K, Major P, Mik M, Pędziwiatr M, Piwowarczyk P, Sierżęga M, Spychalski M, Szczeklik W, Szura M, Wierdak M, Zgodziński W, Budzyński A, Hać S, Jackowski M, Kielan W, Kukla M, Mrowiec S, Myśliwiec P, Sieńko J, Słodkowski M, Tarnowski W, Wallner G, Zawadzki M, Zieniewicz K.   +32 more
europepmc   +1 more source

A Measure of the Impact on Real-Time Patient Care of Evidence-based Medicine Logs. [PDF]

West J Emerg Med
Brown JB, Varadhan AK, Albers JR, Kudrimoti S, Cervantes E, Sgobba P, Yenser DM, Kane BG.   +7 more
europepmc   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source