Results 171 to 180 of about 6,651,869 (248)

Beyond empirically supported treatments: a new contextualized evidence framework for evidence based psychology. [PDF]

Front Psychiatry
Melnik T, Pinto ACPN.
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Developing a validity testing plan for a patient-reported outcome measure in a new context using the argument-based approach to validity. [PDF]

Qual Life Res
Gill SW, Cheng C, Bowman J, Elsworth G, Shaw C, Osborne RH, Hawkins M.   +6 more
europepmc   +1 more source

Speaking evidence to power? An interdisciplinary conversation

South African Journal of Science
Mehita Iqani, Anna Feigenbaum, Laila Asmal, Linsey McGoey, A.M. Kanngieser, Alexander Dunlap, Thema Monroe-White   +6 more
doaj   +1 more source

The ‘burden of evidence' [PDF]

Evidence-Based Spine-Care Journal, 2010
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Evaluating the structure and process of effective integrated care for people with multiple long-term conditions: systematic review protocol. [PDF]

BMJ Open
Todowede O, Damery S, Dracup N, Donoghue J, Butt F, Grove A, Scantlebury A.   +6 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Reinterpreting I² Thresholds: Toward Context-Specific Heterogeneity Assessment in Evidence Synthesis. [PDF]

Cochrane Evid Synth Methods
Martí-Carvajal AJ, Streiner DL.
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source