Results 161 to 170 of about 5,564,521 (297)

Retracted: Evidence Summary of Temperature Management for Comatose Patients after Cardiopulmonary Resuscitation in ICUs. [PDF]

Appl Bionics Biomech, 2023
And Biomechanics AB.
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Dietary Approaches in the Management of Adrenoleukodystrophy: Evidence Summary for Nutritional Tips. [PDF]

Nutrients
Di Stefano A, Ricci L, Ferrari D, Frigerio F, Minnetti M, Fontana M, Donini LM, Isidori AM, Migliaccio S, Poggiogalle E.   +9 more
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Best evidence summary on gastrointestinal function recovery after radical cystectomy for bladder cancer. [PDF]

Asia Pac J Oncol Nurs
Dai Y, Zhang X, Lin Q, Gu X.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Evidence summary of meaning in life intervention for cancer patients. [PDF]

Front Oncol
Yuan P, Lu W, Yong X, Yang W, Zhong X, Wang M, Zhang Y, Fang T, Xie Y, Li X, Zhang L.   +10 more
europepmc   +1 more source

Homelessness, Race/Ethnicity, and Cardiovascular Disease: a State‑of‑the‑Evidence Summary and Structured Review of Race/Ethnicity Reporting. [PDF]

Curr Cardiovasc Risk Rep, 2023
Nyembo PF, Bakker C, Ayenew W, Shroff GR, Busch AM, Vickery KD.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Best Evidence Summary for Perioperative Pain Management in Patients With Pectus Excavatum. [PDF]

Pain Res Manag
Liang Y, Peng H, Huang X, Liang G.
europepmc   +1 more source