Results 171 to 180 of about 5,564,521 (297)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Best evidence summary for self-management of radiodermatitis in head and neck cancer patients: an integrative review. [PDF]

Front Oncol
Cheng L, Zhang M, Zheng Y, Lin L, Xiao T, Zhang M, Huang M, Xu L.   +7 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Best evidence summary for self-management of peristomal skin complications in patients with colorectal cancer and a stoma. [PDF]

Asia Pac J Oncol Nurs
Qin J, Han L, Lv G, You Y, Zhuang H, Ma L.   +5 more
europepmc   +1 more source

Evidence Summary for Nonpharmacological Management of Chemotherapy-Induced Nausea and Vomiting. [PDF]

Biomed Res Int, 2022
Li K, Cai Y, Xie S, Zhou Y, Dong J, Zhu Q, Zhang J, Qiu X.   +7 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Best evidence summary on anticoagulant management in patients with cancer-associated venous thromboembolism. [PDF]

Asia Pac J Oncol Nurs
Xiang X, Yu Y, Fang X, Zheng T, Qiao W.
europepmc   +1 more source

MRI of acute neck infections: evidence summary and pictorial review. [PDF]

Insights Imaging, 2023
Hirvonen J, Heikkinen J, Nyman M, Happonen T, Velhonoja J, Irjala H, Soukka T, Mattila K, Nurminen J.   +8 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Best practices for home nutritional management in postoperative gastric cancer patients: an evidence summary. [PDF]

BMC Cancer
Shanshan W, Lian W, Lu D, Liping L, Peipei L, Juanli Z.   +5 more
europepmc   +1 more source