Results 61 to 70 of about 2,122,545 (262)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Evidence Based Library and Information Practice, 2012 Objective – To discover public library clients’ needs and preferences for modes of training on the use of the Internet and the libraries’ online resources and to apply these findings to improve training offered by public library staff.
Diana K. Wakimoto
doaj +1 more source
Humanitarian Evidence Summary No.17 [PDF]
, 2021 This is the 17th monthly Humanitarian Evidence Summary (HUMES) to signpost FCDO and other UK government departments to the latest relevant evidence and discourse on humanitarian action to inform and support their response. It is the result of 1 day of work per month and is not intended to be a comprehensive summary of available evidence on humanitarian
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Evidence Based Library and Information Practice, 2014 A Review of: Soria, K. M. (2013). Factors predicting the importance of libraries and research activities for undergraduates. Journal of Academic Librarianship, 39(6), 464-470.
Diana K. Wakimoto
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Undergraduates Have Difficulty Distinguishing Formats Based on Discovery Tool Search Results
Evidence Based Library and Information Practice, 2015 A Review of: Gewirtz, S. R., Novak, M., & Parsons, J. (2014). Evaluating the intersection between WorldCat Local and student research. Journal of Web Librarianship, 8(2), 113-124.
Diana K. Wakimoto
doaj +1 more source