Results 121 to 130 of about 11,039,070 (302)

Counterexamples to a Likelihood Theory of Evidence [PDF]

, 2006
The Likelihood Theory of Evidence (LTE) says, roughly, that all the information relevant to the bearing of data on hypotheses (or models) is contained in the likelihoods.
Forster, Malcolm R.
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Conservation Evidence

, 2019
Providing evidence to improve ...
Conservation Evidence
core   +2 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Air pollution concentration fuzzy evaluation based on evidence theory and the K-nearest neighbor algorithm

Frontiers in Environmental Science
Background: Air pollution, characterized by complex spatiotemporal dynamics and inherent uncertainty, poses significant challenges in accurate air quality prediction, and current methodologies often fail to adequately address these complexities.Objective:
Bian Chao, Bian Chao, Huang Guang Qiu
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Facial expression classification based on MPEG-4 FAPs: The use of evidence and prior knowledge for uncertainty removal

, 2004
As low resolution shots, rotations of the head with respect to the camera, face deformation due to speech and so on inflict a great deal of uncertainty in FAP measurements, uncertainty is also inherent in the process of expression analysis.
Kollias, S, Raouzaiou, A, Tsapatsoulis, N, Kollias, Stefanos D., Raouzaiou, Amaryllis, Wallace, M, Wallace, Manolis, Tsapatsoulis, Nicolas   +7 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Financial analysts and collective reputation: Theory and evidence

, 2011
This paper studies the impact of collective reputation on the reporting strategy of experts that face conflicts of interest. The framework we propose applies to different settings involving decision makers that rely on experts for making informed ...
BONINI, STEFANO, SCOTTI, MASSIMO, PAVESI, FILIPPO   +2 more
core