Results 151 to 160 of about 11,039,070 (302)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Evidence-Based Emergency Medicine
, 2008 v.658 hal.; ill.; 27 ...
Evidence-Based Emergency Medicine
core
A classifier-combined method for grading breast cancer based on Dempster-Shafer evidence theory. [PDF]
Quant Imaging Med Surg, 2023 Liu Z +16 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Budget processes: Theory and experimental evidence [PDF]
This paper studies budget processes, both theoretically and experimentally. We compare the outcomes of bottom-up and top-down budget processes. It is often presumed that a top-down budget process leads to a smaller overall budget than a bottom-up budget ...
von Hagen, Jürgen +3 more
core
A new basic probability assignment generation and combination method for conflict data fusion in the evidence theory. [PDF]
Sci Rep, 2023 Tang Y +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Domain Adaptation with Data Uncertainty Measure Based on Evidence Theory. [PDF]
Entropy (Basel), 2022 Lv Y, Zhang B, Zou G, Yue X, Xu Z, Li H.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Situation assessment in air combat considering incomplete frame of discernment in the generalized evidence theory. [PDF]
Sci Rep, 2022 Zhou Y, Tang Y, Zhao X.
europepmc +1 more source