Results 111 to 120 of about 324,438 (264)
The establishment of circumstances and evidences of an accident and their appliction in research [PDF]
Transport, 2003 An accident depends on a lot of factors and circumstances. The estabilishment of factors, different evidences and circumstances are very important for research.
A. Tautkus, A. Jurkauskas
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Unlawfully Obtained Evidences in Turkish Criminal Procedure Law
, 2015 Evidences have a great significance in criminal procedural law to find out material truths. However, there must be some restrictions on obtaining and assessing evidences in a criminal procedure based on the rule of law.
Demiral Bakirman, Busra
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Arab Journal of Forensic Sciences & Forensic MedicineReverse Phase High Performance Liquid Chromatography (RP-HPLC) is an efficient and reliable technique employed in pharmaceutical and forensic analysis.
Khalid Sajjad Feras +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Russian Journal of Economics and Law, 2013 The article views the notion of audit evidences efficiency and proposes the mathematical model based on expert estimations and fuzzy-set theory. The proposed model allows to quantitatively estimate and ground the decision on audit procedures modification
V. A. Yakimova
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Research on electronic evidences-focus on adimissbility of electronic evidences [PDF]
, 2008 随着科技的发展，电子技术的成熟，电子证据也就随之产生；随着计算机和网络的日益普及，电子证据也就越来越普遍；随着我国经济的不断发展，涉及网络知识产权、电子合同纠纷、网络侵犯隐私权、网络与电子商务中的计算机犯罪等民事、行政、刑事案件中也越来越多，电子证据出现的频率越来越高。因此，对于电子证据的准确定位日益显得重要。纵观全文，本文分析了构建电子证据立法框架必须研究的电子证据基本问题，即从电子证据的科学定义、分类定位到立法模式的选择再到证据能力规则的制定最后是其证明力条款 ...
沈轩
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