Results 131 to 140 of about 2,635 (296)
Chapter 7. Evidentiality and epistemic modality in Old Catalan
, 2018 Epistemic modality and evidentiality are two categories that have not been clearly defined in the literature. In order to clarify the boundaries between them, I draw a detailed semantic map for Catalan modal verbs deure (‘must’), haver de (‘have to’) and
Andreu Sentí, Sentí, Andreu
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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Evidentiality in Tukanoan Languages
, 2018 This chapter offers a comprehensive overview of evidentiality in the Tukanoan family of northwestern Amazonia. It begins with the organization of Eastern Tukanoan evidential systems, showing their place within a larger ‘clause modality’ paradigm and in ...
Kristine Stenzel, Elsa Gomez-Imbert
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
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Embedded evidentials in bulgarian
, 2009 We consider evidentials embedded in complement clauses with new data from Bulgarian. For Tibetan, Garrett has shown that embedded evidentials are always shifted to the perspective of the reported speech.
Sauerland, Uli, Schenner, Mathias
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
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Non-Propositional Evidentiality
, 2018 This chapter deals with non-propositional evidentiality, i.e. evidential-like distinctions on markers whose scope is limited to a noun phrase. First, it presents the different types of non-propositional evidential markers, the most common of which are ...
Guillaume Jacques
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