Results 241 to 250 of about 672,774 (331)

Analysing How People Orient to and Spread Rumours in Social Media by Looking at Conversational Threads. [PDF]

PLoS One, 2016
Zubiaga A, Liakata M, Procter R, Wong Sak Hoi G, Tolmie P.   +4 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Discursive construction of the 'scholar' identity: a critical genre analysis of chinese and english academic biographies. [PDF]

Front Psychol
Liu S.
europepmc   +1 more source

Analysis of Intratypic Variation Evident in an Ibaraki Virus Strain and Its Epizootic Hemorrhagic Disease Virus Serogroup

, 2002
Seiichi Ohashi, Kazuo Yoshida, Tohru Yanase, Tomoyuki Tsuda   +3 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Investigating the causal relationship between human blood metabolites and pulmonary hypertension: a two-sample Mendelian randomization study. [PDF]

Front Cardiovasc Med
Zeng X, Zhong B.
europepmc   +1 more source

Expletive agreement, evidentiality, and modality in Logooli

, 2016
John Gluckman, Margit Bowler
semanticscholar   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Bleeding prediction scores in patients with venous thromboembolism using direct oral anticoagulants. [PDF]

Ann Hematol
Wu G, Chen J, Chen Y, Niu P, Chang S, Ma F, Wang C, Lin X, Liu X, Su J, Dai H, Liu Y, Zhang J.   +12 more
europepmc   +1 more source

The evolution of egophoricity and evidentiality in the Himalayas: The case of Bunan

, 2017
Manuel Widmer
semanticscholar   +1 more source