Results 241 to 250 of about 9,314 (300)

Race and Ethnicity and Clinician Linguistic Expressions of Doubt in Hospital Admission Notes.

open access: yesJAMA Netw Open
Lee CR   +7 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

An Efficient Communication Analysis of Modal Typology. [PDF]

open access: yesOpen Mind (Camb)
Imel N, Guo Q, Steinert-Threlkeld S.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Global patterns of genetic admixture reveal effects of language contact

open access: yes
Graff A   +8 more
europepmc   +1 more source
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Evidentiality

Functions of Language, 2009
This article takes up two closely connected theoretical unclarities: the questions of what a linguistic category is, and what it means for linguistic elements to have grammatical rather than lexical status. The two issues are discussed with reference to the case of evidentiality.
Boye, Kasper, Harder, Peter
openaire   +1 more source

Evidentiality

2018
AbstractThis chapter surveys the different ways in which evidentiality is conceived of and referred to. It first outlines the history of the term evidentiality and other terms that have been associated with evidentiality. It then discusses different definitions and ways of understanding evidentiality. Most often evidentiality is defined in terms of the
  +4 more sources

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