Results 151 to 160 of about 984 (297)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
, 2013 This paper draws a link between the typological phenomenon of the paradigmatically supported evidentiality evoked by perfect and/or perfectivity and the equally epistemic system of modal verbs in German.
Abraham, Werner
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The effect of disagreement on children's source memory performance. [PDF]
PLoS One, 2021 Mahr JB, Mascaro O, Mercier H, Csibra G.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Evidentials in the Shuri Dialect of Luchuan (Ryukyuan) [PDF]
, 2011 This dissertation attempts to demonstrate that Luchuan is a language which has a grammatical category of evidentiality. Luchuan is the only sister language of Japanese; however, since they are considered to have diverged as early as the beginning of ...
Arakaki, Tomoko
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Combining observational and experimental approaches to the development of language and communication in rural samples: Opportunities and challenges. [PDF]
J Child Lang, 2023 Cristia A +5 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Evidentials and metarepresentation in early child language
, 2009 This paper examines the developmental relation of the use and understanding of Modern Greek evidential lexical items with varying degrees of metarepresentational ability.
Ifantidou, E.
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Evidentials in Interrogatives: A Case Study of Korean
, 2019 This paper concerns a puzzle about the interpretation of Korean directevidential -te- in interrogatives which I call evidential perspective shift in questions (‘origo shift of evidentials’ in quesitons in Garrett 2001).
Lim, Dongsik
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