Results 31 to 40 of about 257,790 (298)

Behavioral control and changes in brain activity of honeybee during flapping

open access: yesBrain and Behavior, 2021
Introduction Insect cyborg is a kind of novel robot based on insect–machine interface and principles of neurobiology. The key idea is to stimulate live insects by specific stimuli; thus, the flight trajectory of insects could be controlled as anticipated.
Haojia Ding, Jieliang Zhao, Shaoze Yan
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Reduced auditory perception and brain response with quiet TMS coil

open access: yesBrain Stimulation
Background: Electromagnetic forces in transcranial magnetic stimulation (TMS) coils generate a loud clicking sound that produces confounding auditory activation and is potentially hazardous to hearing.
David L.K. Murphy   +6 more
doaj   +1 more source

Attenuation of Hippocampal Evoked Potentials in vivo by Activation of GtACR2, an Optogenetic Chloride Channel

open access: yesFrontiers in Neuroscience, 2021
AimGtACR2, a light-activated chloride channel, is an attractive tool for neural inhibition as it can shunt membrane depolarizations. In this study, we assessed the effect of activating GtACR2 on in vivo hippocampal CA1 activity evoked by Schaffer ...
Anirudh R. Acharya   +8 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

N2b Reflects the Cognitive Changes in Executive Functioning After Concussion: A Scoping Review

open access: yesFrontiers in Human Neuroscience, 2020
Objectives: The N2b is an event-related potential (ERP) component thought to index higher-order executive function. While the impact of concussion on executive functioning is frequently discussed in the literature, limited research has been done on the ...
Sophie N. Krokhine   +10 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

The value of brainstem evoked potential in clinical decision of a patient with hypoxic-ischemic encephalopathy O valor do potencial evocado auditivo em decisão clínica em paciente com síndrome hipóxico-isquêmica

open access: yesArquivos de Neuro-Psiquiatria, 2007
Establishing a prognosis for hypoxic-ischemic encephalopathy during the neonatal period is extremely difficult, as the neuroplasticity of the developing brain makes it almost impossible to measure the affected area.
Anna Lecticia R. Pinto   +1 more
doaj   +1 more source

Role of pain-related evoked potential in the diagnosis of meralgia paresthetica

open access: yesAnnals of Indian Academy of Neurology, 2021
Introduction: Entrapment of the lateral femoral cutaneous nerve (LFCN) of thigh results in meralgia paresthetica (MP). Standard electrophysiological tests for MP are technically demanding and unreliable.
Atif Iqbal Ahmed Shaikh   +12 more
doaj   +1 more source

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