Results 241 to 250 of about 147,429 (300)

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

Advanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu, Jiaxin Zhang, Xiangyu Yan, Nuo Li, Yu‐Chao Dong, Zihao Wang, Daowei Li, Yong Du, Huan Wang   +8 more
wiley   +1 more source

From demyelination to neurodegeneration in multiple sclerosis: reassessing the role of visual evoked potential P100-N145 amplitudes: a missing piece of the puzzle? [PDF]

Front Neurol
Kaya Tutar N, Kale N.
europepmc   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

Eye metrics often reflect visual conscious awareness, conscious content, and neural processing in cerebral blindness. [PDF]

Commun Biol
Kronemer SI, Gobo VE, Japee S, Merriam EP, Osborne B, Bandettini PA, Liu TT.   +6 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Comparison of Physiological Brain Responses Evoked by Visual and Electrical Stimulation. [PDF]

Invest Ophthalmol Vis Sci
Kordecka K, Kublik E, Foik AT.
europepmc   +1 more source

Revealing Pathological Auditory Central Inhibition in Tinnitus Using Cortical Auditory Evoked Potentials Responses to Contralateral Acoustic Stimulation. [PDF]

Brain Behav
Qian Z, Qixuan W, Wenling J, Yiting W, Haifeng L, Meiping H, Lu Y, Yan R, Haibin S, Bei L, Zhiwu H.   +10 more
europepmc   +1 more source

Atypical visual field defect without major compression from an inflammatory Rathke's cleft cyst: illustrative case. [PDF]

J Neurosurg Case Lessons
Ohnishi S, Nakase K, Nishimura F, Morisaki Y, Yokoyama S, Kotsugi M, Matsuda R, Takeshima Y, Yamada S, Park YS, Nakagawa I.   +10 more
europepmc   +1 more source

Perceived sensorimotor synchrony enhances pain modulation and attenuates laser-evoked potentials. [PDF]

Commun Biol
Pan X, Xiao Y, Hu L, Lu X.
europepmc   +1 more source

Luminance noise impacts putative luminance components of visual evoked potentials but not chromatic components. [PDF]

Psicol Reflex Crit
Lopes BB, Loureiro TMG, da Costa Brito FA, Miquilini L, Brasil A, Costa MF, Salomão RC, Ventura DF, Brino AL, da Silva Souza G.   +9 more
europepmc   +1 more source