Results 51 to 60 of about 494,653 (342)

The pain matrix reloaded: a salience detection system for the body [PDF]

open access: yes, 2011
Neuroimaging and neurophysiological studies have shown that nociceptive stimuli elia salience detection system for the bodycit responses in an extensive cortical network including somatosensory, insular and cingulate areas, as well as frontal and ...
Iannetti, Gian Domenico   +3 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]

open access: yes, 2009
Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G.   +2 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Visual evoked potentials in patients after methanol poisoning

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2016
Objectives: We report the results of the visual evoked potentials (VEP) examination in patients after severe poisoning by methanol. Material and Methods: The group of 47 patients (38 males and 9 females) was assembled out of persons who survived an ...
Pavel Urban   +4 more
doaj   +1 more source

Visually induced analgesia: seeing the body reduces pain [PDF]

open access: yes, 2009
Given previous reports of strong interactions between vision and somatic senses, we investigated whether vision of the body modulates pain perception. Participants looked into a mirror aligned with their body midline at either the reflection of their own
Aglioti, S.M.   +3 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Clinical and electrophysiological correlation in patient with optic neuritis

open access: yesRevista Cubana de Investigaciones Biomédicas, 2020
Introduction: Optic neuritis is a disorder frequently find in our environment. Material and methods: A descriptive and traverse study was performed in patients with diagnosis of optic neuritis,  that attended  to the neurophthalmology service of the ...
Lianne Alicia Chang Arraño   +3 more
doaj  

Theta synchronization over occipito‐temporal cortices during visual perception of body parts [PDF]

open access: yes, 2018
Categorical clustering in the visual system is thought to have evolved as a function of intrinsic (intra-areal) and extrinsic (interareal) connectivity and experience.
Aglioti, S   +3 more
core   +1 more source

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

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