Results 91 to 100 of about 265,071 (296)

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

Brainstem auditory evoked responses in an equine patient population. Part II: foals. [PDF]

, 2014
BackgroundReports of the use of brainstem auditory evoked response (BAER) as a diagnostic modality in foals have been limited.Hypothesis/objectivesTo describe BAER findings and associated causes of hearing loss in foals.AnimalsStudy group 18 foals (15 ...
Aleman, M, Holliday, TA, Madigan, JE, Williams, DC   +3 more
core   +1 more source

Multimodal evoked potentials and transcranial magnetic stimulation in diagnostics of children with encephalitis, acute disseminated encephalomyelitis and multiple sclerosis

Русский журнал детской неврологии, 2018
Background. The growing incidence of such central nervous system disorders as encephalitis (EP), acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS) in pediatric population, similarity of their clinical manifestations at the onset ...
E. Yu. Skripchenko, A. V. Klimkin, V. B. Voitenkov, N. V. Skripchenko, A. V. Surovtseva   +4 more
doaj   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Predictive Performance of Machine Learning with Evoked Potentials for SCI and MS Prognosis: A Meta-Analysis

Clinical and Translational Neuroscience
Evoked potentials (EPs), including somatosensory evoked potentials (SSEPs) and motor evoked potentials (MEPs), are used to assess neural conduction in spinal cord injury (SCI) and multiple sclerosis (MS), conditions marked by demyelination, inflammation,
Constantinos Koutsojannis, Dionysia Chrysanthakopoulou   +1 more
doaj   +1 more source

HEARING IMPAIRMENT IN CHILDREN WITH PERINATAL INJURIES OF CENTRAL NERVOUS SYSTEM

Вопросы современной педиатрии, 2012
The results of two-stage audiologic examination (otoacoustic emissions method and assessment of auditory evoked potentials) of 74 term and premature newborns are shown in this article.
E. V. Shishkinskaya, I. A. Belyaeva, E. P. Bombardirova, N. Yu. Semenova   +3 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Visually induced analgesia: seeing the body reduces pain [PDF]

, 2009
Given previous reports of strong interactions between vision and somatic senses, we investigated whether vision of the body modulates pain perception. Participants looked into a mirror aligned with their body midline at either the reflection of their own
Aglioti, S.M., Betti, V., Haggard, P., Longo, Matthew R.   +3 more
core   +1 more source

Potencial evocado auditivo cortical em neonatos a termo e pré-termo: gênero e indicadores de risco para deficiência auditiva

Audiology: Communication Research, 2016
RESUMO Objetivo Pesquisar os potenciais exógenos em neonatos normo-ouvintes, nascidos a termo e pré-termo, correlacionando-os ao gênero e presença de Indicadores de Risco para Deficiência Auditiva (IRDA).
Ândrea de Melo, Pricila Sleifer, Inaê Costa Rechia, Eliara Pinto Vieira Biaggio   +3 more
doaj   +1 more source