Results 81 to 90 of about 11,057,450 (337)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Predictive Performance of Machine Learning with Evoked Potentials for SCI and MS Prognosis: A Meta-Analysis

Clinical and Translational Neuroscience
Evoked potentials (EPs), including somatosensory evoked potentials (SSEPs) and motor evoked potentials (MEPs), are used to assess neural conduction in spinal cord injury (SCI) and multiple sclerosis (MS), conditions marked by demyelination, inflammation,
Constantinos Koutsojannis, Dionysia Chrysanthakopoulou   +1 more
doaj   +1 more source

HEARING IMPAIRMENT IN CHILDREN WITH PERINATAL INJURIES OF CENTRAL NERVOUS SYSTEM

Вопросы современной педиатрии, 2012
The results of two-stage audiologic examination (otoacoustic emissions method and assessment of auditory evoked potentials) of 74 term and premature newborns are shown in this article.
E. V. Shishkinskaya, I. A. Belyaeva, E. P. Bombardirova, N. Yu. Semenova   +3 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Temporal interference stimulation evoked neural local field potential oscillations in-vivo

, 2023
Xiaoqi Zhu, Jonathon Howard, Zack Bailey, Adam Williamson, Rylie A. Green, Eric Daniel Głowacki, Nir Grossman   +6 more
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Potencial evocado auditivo cortical em neonatos a termo e pré-termo: gênero e indicadores de risco para deficiência auditiva

Audiology: Communication Research, 2016
RESUMO Objetivo Pesquisar os potenciais exógenos em neonatos normo-ouvintes, nascidos a termo e pré-termo, correlacionando-os ao gênero e presença de Indicadores de Risco para Deficiência Auditiva (IRDA).
Ândrea de Melo, Pricila Sleifer, Inaê Costa Rechia, Eliara Pinto Vieira Biaggio   +3 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Comparison between the lambda response of eye-fixation-related potentials and the P100 component of pattern-reversal visual evoked potentials [PDF]

, 2003
Koji Kazai, A. Yagi
openalex   +1 more source

Refractory episodic vertigo: role of intratympanic gentamicin and vestibular evoked myogenic potentials,

Brazilian Journal of Otorhinolaryngology
Introduction: Even today, the treatment of intractable vertigo remains a challenge. Vestibular ablation with intratympanic gentamicin stands as a good alternative in the management of refractory vertigo patients.
Erika Celis-Aguilar, Ramon Hinojosa-González, Olivia Vales-Hidalgo, Heloisa Coutinho-Toledo   +3 more
doaj   +1 more source