Results 111 to 120 of about 2,360,167 (299)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The morphology and evolution of channels on the Wax Lake Delta, Louisiana, USA [PDF]

, 2013
John Shaw, David Mohrig, Spencer Whitman
openalex   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Evidence of neolithic cannibalism among farming communities at El Mirador cave, Sierra de Atapuerca, Spain

Scientific Reports
In El Mirador cave in Sierra de Atapuerca, Spain, a unique collection of human remains provides insights into cannibalistic practices from the Neolithic to the Bronze Age.
Palmira Saladié, Francesc Marginedas, Juan Ignacio Morales, Josep María Vergès, Ethel Allué, Isabel Expósito, Marina Lozano, Patricia Martín, Javier Iglesias-Bexiga, Marta Fontanals, Roser Marsal, Raquel Hernando, Aitor Burguet-Coca, Antonio Rodríguez-Hidalgo   +13 more
doaj   +1 more source

Microbial Degradation of Plastic in Aqueous Solutions Demonstrated by CO2 Evolution and Quantification [PDF]

, 2020
Ruth‐Sarah Rose, Katherine H. Richardson, Elmeri Johannes Latvanen, China A. Hanson, Marina Resmini, Ian A. Sanders   +5 more
openalex   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

HSP90 as an evolutionary capacitor drives adaptive eye size reduction via atonal

Nature Communications
Genetic variation fuels evolution, and the release of cryptic variation is key for adaptation. The heat shock protein 90 (HSP90) has been proposed to act as an evolutionary capacitor by revealing such hidden variation under stress.
Rascha Sayed, Özge Şahin, Mohammed Errbii, Reshma R, Robert Peuß, Tobias Prüser, Lukas Schrader, Nora K. E. Schulz, Joachim Kurtz   +8 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Structural insights into the mechanism and evolution of the vaccinia virus mRNA cap N7 methyl‐transferase [PDF]

, 2007
Marcos de la Peña, O.J.P. Kyrieleis, S. Cusack   +2 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source