Results 151 to 160 of about 10,424,499 (417)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

The Hereditary Mechanism and the Search for the Unknown Factors of Evolution [PDF]

, 1895
henry Fairfield Osborn
openalex   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Can Chimpanzee Biology Highlight Human Origin and Evolution?

Rambam Maimonides Medical Journal, 2010
The closest living relatives of humans are their chimpanzee/bonobo (Pan) sister species, members of the same subfamily “Homininae”. This classification is supported by over 50 years of research in the fields of chimpanzee cultural diversity, language ...
Itai Roffman, Eviatar Nevo
doaj   +1 more source

The evolution of SARS-CoV-2

Nature Reviews Microbiology, 2023
P. V. Markov, M. Ghafari, M. Beer, K. Lythgoe, P. Simmonds, N. Stilianakis, A. Katzourakis   +6 more
semanticscholar   +1 more source

Galapagos evolution continues [PDF]

, 1983
Summary of symposium "Evolution in the Galapagos" held December 8, 1982 in ...
Boag, Peter T.
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Despite plasticity, heatwaves are costly for a coral reef fish

Scientific Reports
Climate change is intensifying extreme weather events, including marine heatwaves, which are prolonged periods of anomalously high sea surface temperature that pose a novel threat to aquatic animals.
Jacey C. Van Wert, Kim Birnie-Gauvin, Jordan Gallagher, Emily A. Hardison, Kaitlyn Landfield, Deron E. Burkepile, Erika J. Eliason   +6 more
doaj   +1 more source

The coincidence of ecological opportunity with hybridization explains rapid adaptive radiation in Lake Mweru cichlid fishes

Nature Communications, 2019
Recent studies have suggested that hybridization can facilitate adaptive radiations. Here, the authors show that opportunity for hybridization differentiates Lake Mweru, where cichlids radiated, and Lake Bangweulu, where cichlids did not radiate despite ...
Joana I. Meier, Rike B. Stelkens, Domino A. Joyce, Salome Mwaiko, Numel Phiri, Ulrich K. Schliewen, Oliver M. Selz, Catherine E. Wagner, Cyprian Katongo, Ole Seehausen   +9 more
doaj   +1 more source

The Evolution of the Religion of Israel: III. The Prophets of the Eighth Century [PDF]

, 1912
George A. Barton
openalex   +1 more source