Results 181 to 190 of about 10,682,507 (345)

Some Suggestions on the Origin and Evolution of Web-Spinning in Spiders [PDF]

, 1895
R.I. Pocock
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Chance and purpose in the evolution of biospheres. [PDF]

Philos Trans R Soc Lond B Biol Sci
Donoghue PCJ, Lenton TM, Okasha S, Shields GA, Spang A.   +4 more
europepmc   +1 more source

On the Evolution of Heat During Muscular Action 1 [PDF]

, 1878
Percy Faraday Frankland
openalex   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Bioenergetics evolution: the link between Earth's and Life's history. [PDF]

Philos Trans R Soc Lond B Biol Sci
Padalko A, Karavaeva V, Zamarreno Beas J, Neukirchen S, Sousa FL.   +4 more
europepmc   +1 more source

Radium and the Evolution of the Earth's Crust [PDF]

, 1913
Arthur Holmes
openalex   +1 more source

Completely Derandomized Self-Adaptation in Evolution Strategies

Evolutionary Computation, 2001
N. Hansen, A. Ostermeier
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Cultural Incentive Learning: How Culture Shapes Acquisition of Values. [PDF]

Evol Anthropol
Rigoli F, Lennon J.
europepmc   +1 more source