Results 201 to 210 of about 10,682,507 (345)
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Time of proto-Earth reservoir formation and volatile element depletion from <sup>53</sup>Mn-<sup>53</sup>Cr chronometry. [PDF]
Kruttasch PM, Mezger K.
europepmc +1 more source
The Mystery of Space. A Study of the Hyperspace Movement in the Light of the Evolution of New Psychic Faculties and An Inquiry into the Genesis and Essential Nature of Space. [PDF]
R. T. Browne
openalex +1 more source
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh+8 more
wiley +1 more source
The rx3 Gene Contributes to the Evolution of Eye Loss in the Cavefish Astyanax mexicanus. [PDF]
Shennard D+5 more
europepmc +1 more source
On seeing in the dark: Remarks on the evolution of the eye. [PDF]
Oskar Nagel
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
On the emergence of metabolism: the evolution of proteins that powered life. [PDF]
Nanda V+11 more
europepmc +1 more source