Results 281 to 290 of about 8,690,713 (332)

Technology Evolution [PDF]

Joshua L. Rosenbloom
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Sequential crystallization pathways in apatite-wollastonite glass-ceramics <i>via</i> spray pyrolysis. [PDF]

RSC Adv
Workie AB, Taye MB.
europepmc   +1 more source

Kerikeri 'gold' : a behavioural investigation of the process involved in the evolution of spatial patterning and the 'personalité' of Kerikeri, Bay of Islands : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Geography at Massey University

, 1971
Christine Elizabeth Pearson Elson-White
openalex   +1 more source

Correction to: Strong Positive Selection in Aedes aegypti and the Rapid Evolution of Insecticide Resistance. [PDF]

Mol Biol Evol
europepmc   +1 more source

Active control of forward/backward charge transfer in Z-scheme water splitting: manipulating electrostatic affinity/repulsion between photocatalyst surface and electron mediator. [PDF]

Chem Sci
Itagaki R, Nakada A, Suzuki H, Tomita O, Abe R.   +4 more
europepmc   +1 more source

Degrees of convergent evolution in rodent adaptations to arid environments. [PDF]

Genome Res
Chalopin D, Rey C, Ganofsky J, Blin J, Chevret P, Mouginot M, Guéguen L, Boussau B, Pantalacci S, Sémon M.   +9 more
europepmc   +1 more source

EMBO Press co-evolves with molecular ecology and evolutionary biology. [PDF]

EMBO J
Moran Y, Coelho SM, Ettema TJG, Feschotte C, Kaltenpoth M, Khila A, Laine AL, Liow LH, Petrov D, Ramakrishnan U, Sarkies P, Srivastava M, Voolstra C, Pulverer B.   +13 more
europepmc   +1 more source