Results 41 to 50 of about 3,400,526 (308)

Microscopic Malaria Infection and Its Determinants in Urban and Rural Populations Living in South-East Gabon

Journal of Parasitology Research
A better understanding of malaria epidemiology in both asymptomatic and symptomatic individuals is essential for developing strategies to control the disease.
Jean-Claude Biteghe-Bi-Essone, Roméo Karl Imboumy-Limoukou, Steede-Seinnat Ontoua, Nick Atiga, Nancy Mbani-Mpega, Lady Charlène Kouna, Jean Bernard Lekana-Douki, Lydie Sandrine Oyegue-Liabagui   +7 more
doaj   +1 more source

DNA Polymerases Engineered by Directed Evolution to Incorporate Nonstandard Nucleotides

Frontiers in Microbiology, 2014
DNA polymerases have evolved for billions of years to accept natural nucleoside triphosphate substrates with high fidelity and to exclude closely related structures, such as the analogous ribonucleoside triphosphates. However, polymerases that can accept
Roberto eLaos, John Michael Thomson, Steven Albert Benner   +2 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Deconstructing the geography of human impacts on species’ natural distribution

Nature Communications
It remains unknown how species’ populations across their geographic range are constrained by multiple coincident natural and anthropogenic environmental gradients.
Conor Waldock, Bernhard Wegscheider, Dario Josi, Bárbara Borges Calegari, Jakob Brodersen, Luiz Jardim de Queiroz, Ole Seehausen   +6 more
doaj   +1 more source

Genomic architecture of adaptive radiation and hybridization in Alpine whitefish

Nature Communications, 2022
In this genomic study on Alpine whitefish radiations, the authors reveal details on the genetic architecture underlying the repeated eco-morphological diversification and the role of hybridization in the evolution of endemic whitefish species.
Rishi De-Kayne, Oliver M. Selz, David A. Marques, David Frei, Ole Seehausen, Philine G. D. Feulner   +5 more
doaj   +1 more source

Systematic errors in orthology inference and their effects on evolutionary analyses

iScience, 2021
Summary: The availability of complete sets of genes from many organisms makes it possible to identify genes unique to (or lost from) certain clades. This information is used to reconstruct phylogenetic trees; identify genes involved in the evolution of ...
Paschalis Natsidis, Paschalia Kapli, Philipp H. Schiffer, Maximilian J. Telford   +3 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria [PDF]

, 2015
Although prokaryotes are usually classified using molecular phylogenies instead of phenotypes after the advent of gene sequencing, neither of these methods is satisfactory because the phenotypes cannot explain the molecular trees and the trees do not fit
Pu, Yiyi, Sarna, Brooke, Sinsheimer, Janet S., Larsen, Joseph, de la Haba, Rafael R., de la Haba, Rafael R, Ruiz de la Haba, Rafael, Lake, James A., Lake, James A, Zhao, Jun, Sinsheimer, Janet S, Koo, Hyun-min, Koo, HyunMin   +12 more
core   +1 more source

Evolutionary and Expression Analyses Show Co-option of khdrbs Genes for Origin of Vertebrate Brain

Frontiers in Genetics, 2018
Genes generated by whole genome duplications (WGD) can be co-opted by changing their regulation process or altering their coding proteins, which has been shown contributable to the emergence of vertebrate morphological novelties such as vertebrate ...
Su Wang, Su Wang, Qingyun Yang, Qingyun Yang, Ziyue Wang, Ziyue Wang, Shuoqi Feng, Shuoqi Feng, Hongyan Li, Hongyan Li, Dongrui Ji, Dongrui Ji, Shicui Zhang, Shicui Zhang   +13 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source