Results 81 to 90 of about 2,325,018 (299)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Repeated loss of function at HD mating-type genes and of recombination in anther-smut fungi

Nature Communications
Basidiomycete fungi typically have two mating-type loci controlling mating compatibility, HD and PR, residing on different chromosomes. Loss-of-function in mating compatibility has been reported at the PR genes in a few heterothallic basidiomycetes, but ...
Elise A. Lucotte, Paul Jay, Quentin Rougemont, Loreleï Boyer, Amandine Cornille, Alodie Snirc, Amandine Labat, Elizabeth Chahine, Marine Duhamel, Alice Namias, Jacob Gendelman, Wen-Juan Ma, Roxanne K. Hayes, Shikhi Baruri, Joseph P. Ham, Michael H. Perlin, Michael E. Hood, Ricardo C. Rodríguez de la Vega, Tatiana Giraud   +18 more
doaj   +1 more source

Elusive data underlying debate at the prokaryote-eukaryote divide

Biology Direct, 2018
Background The origin of eukaryotic cells was an important transition in evolution. The factors underlying the origin and evolutionary success of the eukaryote lineage are still discussed.
Marie Gerlitz, Michael Knopp, Nils Kapust, Joana C. Xavier, William F. Martin   +4 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Evolutionary and developmental dynamics of sex-biased gene expression in common frogs with proto-Y chromosomes

Genome Biology, 2018
Background The patterns of gene expression on highly differentiated sex chromosomes differ drastically from those on autosomes, due to sex-specific patterns of selection and inheritance.
Wen-Juan Ma, Paris Veltsos, Roberto Sermier, Darren J Parker, Nicolas Perrin   +4 more
doaj   +1 more source

300 million years of diversification: elucidating the patterns of orthopteran evolution based on comprehensive taxon and gene sampling [PDF]

, 2015
Hojun Song, Christiane Amédégnato, María Marta Cigliano, Laure Desutter‐Grandcolas, Sam W. Heads, Yuan Huang, Daniel Otte, Michael F. Whiting   +7 more
openalex   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The coincidence of ecological opportunity with hybridization explains rapid adaptive radiation in Lake Mweru cichlid fishes

Nature Communications, 2019
Recent studies have suggested that hybridization can facilitate adaptive radiations. Here, the authors show that opportunity for hybridization differentiates Lake Mweru, where cichlids radiated, and Lake Bangweulu, where cichlids did not radiate despite ...
Joana I. Meier, Rike B. Stelkens, Domino A. Joyce, Salome Mwaiko, Numel Phiri, Ulrich K. Schliewen, Oliver M. Selz, Catherine E. Wagner, Cyprian Katongo, Ole Seehausen   +9 more
doaj   +1 more source

The Evolution of X‐Ray Emission in Young Stars [PDF]

, 2005
T. Preibisch, Eric D. Feigelson
openalex   +1 more source