Results 81 to 90 of about 10,682,507 (345)

FastTree: Computing Large Minimum Evolution Trees with Profiles instead of a Distance Matrix

Molecular biology and evolution, 2009
Gene families are growing rapidly, but standard methods for inferring phylogenies do not scale to alignments with over 10,000 sequences. We present FastTree, a method for constructing large phylogenies and for estimating their reliability.
M. Price, Paramvir S. Dehal, A. Arkin
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Regulatory and disruptive variants in the CLCN2 gene are associated with modified skin color pattern phenotypes in the corn snake

Genome Biology
Background Snakes exhibit a broad variety of adaptive colors and color patterns, generated by the spatial arrangement of chromatophores, but little is known of the mechanisms responsible for these spectacular traits.
Sophie A. Montandon, Pierre Beaudier, Asier Ullate-Agote, Pierre-Yves Helleboid, Maya Kummrow, Sergi Roig-Puiggros, Denis Jabaudon, Leif Andersson, Michel C. Milinkovitch, Athanasia C. Tzika   +9 more
doaj   +1 more source

Taxonomic novelties and new records of Fennoscandian crustose lichens

MycoKeys, 2017
We present taxonomic, distributional and ecological notes on Fennoscandian crustose lichens and lichenicolous fungi, based on new collections as well as revision of herbarium material. Two new combinations are proposed: Frutidella furfuracea comb.
Måns Svensson, Stefan Ekman, Jon T. Klepsland, Anders Nordin, Göran Thor, Gesa von Hirschheydt, Fredrik Jonsson, Tommy Knutsson, Mattias Lif, Toby Spribille, Martin Westberg   +10 more
doaj   +3 more sources

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Fossil-calibrated molecular phylogeny of atlantid heteropods (Gastropoda, Pterotracheoidea)

BMC Evolutionary Biology, 2020
Background The aragonite shelled, planktonic gastropod family Atlantidae (shelled heteropods) is likely to be one of the first groups to be impacted by imminent ocean changes, including ocean warming and ocean acidification. With a fossil record spanning
Deborah Wall-Palmer, Arie W. Janssen, Erica Goetze, Le Qin Choo, Lisette Mekkes, Katja T. C. A. Peijnenburg   +5 more
doaj   +1 more source

BL Lac evolution revisited

, 2004
BL Lac objects are an elusive and rare class of active galactic nuclei. For years their evolutionary behavior has appeared inconsistent with the trend observed in the population of AGN at large.
Cavallotti, Francesca, Rector, Travis, Stocke, John T., Wolter, Anna   +3 more
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Cultural replication and microbial evolution [PDF]

, 2014
The aim of this paper is to argue that cultural evolution is in many ways much more similar to microbial than to macrobial biological evolution.
Nanay, Bence
core  

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source