Results 161 to 170 of about 169,626 (311)

Well-posedness and stability results for nonlinear abstract evolution equations with time delays

, 2018
International audienceWe consider abstract evolution equations with a nonlinear term depending on the state and on delayed states. We show that, if the -semigroup describing the linear part of the model is exponentially stable, then the whole system ...
Pignotti, Cristina, Nicaise, Serge, Cristina Pignotti, Serge Nicaise   +3 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Kallman-Rota Inequality for Evolution Semigroups

, 2002
A Kallman-Rota type inequality for evolution semigroups and applications for real valued functions are ...
Dragomir, Sever S, Buşe, Constantin
core  

The Nonlinear Schrödinger Equation Derived From the Fifth-Order Korteweg–de Vries Equation Using Multiple Scales Method

International Journal of Differential Equations
The mathematical models of problems that arise in many branches of science are nonlinear equations of evolution (NLEE). For this reason, NLEE have served as a language in formulating many engineering and scientific problems.
Murat Koparan
doaj   +1 more source

Evolution Equations for Quantum Semi-Markov Dynamics. [PDF]

Entropy (Basel), 2020
Megier N, Smirne A, Vacchini B.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

First-order inverse evolution equations

, 2014
New results on identification problems for evolution systems of both hyperbolic and parabolic type are described together with some concrete applications to partial differential ...
Al Horani M., FAVINI, ANGELO
core  

Remarks on Nonlinear Evolution Equations

Journal of Mathematical Analysis and Applications, 1996
In the paper fully nonlinear evolution equations \[ {du \over dt} +A(t,u,u) = 0, \quad 0\leq t\leq T,\quad u(0) =\varphi, \] in a Banach space \(X\) are considered. Here \(T>0\), \(A\) is a nonlinear mapping of a subset \(D(A) \subset [0,T] \times X \times X\) into \(X\) and \(\varphi \in X\).
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source