Results 111 to 120 of about 25,148 (310)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

On nonlinear, nonconvex evolution inclusions

Kodai Mathematical Journal, 1995
The paper contrasts the sets \(S(x_0)\) and \(S_e(x_0)\) of integral solutions of Benilan to the differential systems \(- x'(t)\in Ax(t)+ F(t, x(t))\), \(x(0)= x_0\) and \(-x'(t)\in Ax(t)+ \text{ext } F(t, x(t))\), \(x(0)= x_0\) respectively, where ext stands for the set of extreme points. The main results state that, for every \(x_0\in \overline D\), \
Hu, Shou Chuan, Papageorgiou, Nikolaos S.   +1 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Volatile evolution of magma in the Campi Flegrei (Italy) volcanic system based on melt inclusions. [PDF]

, 2012
La comunicazione riporta i risultati di indagini sperimentali su melt inclusions nei prodotti magmatici dei Campi ...
ESPOSITO R., KLEBESZ, RITA, DE VIVO, BENEDETTO, BODNAR R. J.   +3 more
core  

Corrosion Damage Analysis and Material Characterization of Sherman and Centaur - The Historic Military Tanks [PDF]

, 2013
A study of corrosion damage and material characterization of two historic military tanks, the Sherman and Centaur is reported. Experiments were conducted to analyse surface corrosion and corrosion propagation from surface to sub-surface.
Saeed, Adil, Khan, Zulfiqar Ahmad, Montgomery, E.L.   +2 more
core   +1 more source

Optimal Control of Semilinear Unbounded Evolution Inclusions with Functional Constraints [PDF]

, 2015
This paper is devoted to the study of a Mayer-type optimal control problem for semilinear unbounded evolution inclusions in reflexive and separable Banach spaces subject to endpoint constraints described by finitely many Lipschitzian equalities and ...
Wang, Dong, Mordukhovich, Boris S.
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Parametrized relaxation for evolution inclusions of the subdifferential type [PDF]

, 1995
summary:In this paper we consider parametric nonlinear evolution inclusions driven by time-dependent subdifferentials. First we prove some continuous dependence results for the solution set (of both the convex and nonconvex problems) and for the set of ...
Papageorgiou, Nikolaos S., Nikolaos S. Papageorgiou   +1 more
core