Effect of Rare Earth Elements (La and Ce) on Microstructure and Mechanical Properties of U75V Steel. [PDF]
Hu M, Ren L, Feng G, Yang J, Liu Y.
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Advanced Stainless Steel-From Making, Shaping, Treating to Products. [PDF]
Chen C, Xue Z, Mu W.
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Cretaceous Volatile Fluxes from Intermediate-Acid Volcanism in NE China: Climatic Perturbations Triggered by Songliao Basin Magmatism (117-119 Ma). [PDF]
Wang Y, He W, Shan X.
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
High-temperature wood silicification: constraints from fluid and carbonaceous inclusions in quartz from Qitai, NW China. [PDF]
Liu W +9 more
europepmc +1 more source
VIABLE SOLUTIONS FOR EVOLUTION INCLUSIONS
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Phanerozoic seawater Mg/Ca variations driven by supercontinent cycles. [PDF]
Zhang P +4 more
europepmc +1 more source

