Results 161 to 170 of about 4,624,942 (322)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Concept Evolution in Information System Evolution [PDF]

open access: yes, 2004
Contains fulltext : 60241.pdf (author's version ) (Open Access)
Proper, H.A., Hoppenbrouwers, S.J.B.A.
openaire  

Modeling the co-evolution of natural, economic and governance subsystems in integrated agri-ecological systems: Perspectives and challenges✰

open access: gold, 2019
Charlotte Gerling   +8 more
openalex   +2 more sources

Periodic Pattern of Genetic and Fitness Diversity during Evolution of an Artificial Cell-Like System [PDF]

open access: bronze, 2015
Norikazu Ichihashi   +4 more
openalex   +1 more source

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