Results 51 to 60 of about 27,661,028 (295)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Marine sediments are recognized as crucial reservoirs of antibiotic resistance genes (ARGs). However, the antibiotic resistome in sediments of the East China Sea, an area heavily impacted by human activities, has not been thoroughly studied.
Xiaozhong Chen +6 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Controllability of nonlinear differential evolution systems in a separable Banach space
In this article, we study the controllability of semilinear evolution differential systems with nonlocal initial conditions in a separable Banach space. The results are obtained by using Hausdorff measure of noncompactness and a new calculation method.
Bheeman Radhakrishnan +1 more
doaj
On a $p$-Laplacian type of evolution system and applications to the Bean model in the type-II superconductivity theory [PDF]
We study the Cauchy problem for an $p$-Laplacian type of evolution system ${\mathbf H}_{t}+\g [ | \g {\mathbf H}|^{p-2} \g {\mathbf H}|]={\mathbf F}$.
H. Yin
semanticscholar +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Charting mobility patterns in the scientific knowledge landscape
From small steps to great leaps, metaphors of spatial mobility abound to describe discovery processes. Here, we ground these ideas in formal terms by systematically studying mobility patterns in the scientific knowledge landscape.
Chakresh Kumar Singh +4 more
doaj +1 more source
Model evolution and system evolution
In this paper we define an evolution mechanism with formal semantics using the metamodeling methodology [Geisler et al.98] based on dynamic logic. A remarkable feature of the metamodeling methodology is the ability to define the relation of intentional and extensional entities within one level, allowing not only for the description of structural ...
Pons, Claudia +2 more
openaire +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Nitrite oxidation, a pivotal process in the nitrogen cycle driven by microorganisms, is primarily carried out by nitrite-oxidizing bacteria (NOB). While extensive studies on Nitrospira have been conducted in terrestrial habitats, knowledge of Nitrospira ...
Hao Dong, Hui He, Min Wang
doaj +1 more source

