Results 161 to 170 of about 85,786 (301)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Evolution of incretin-based therapies: From GLP-1 monotherapy to dual and triple agonists: A new era in metabolic therapy. [PDF]

Indian J Med Res
Gupta M, Shukla J.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

A bibliometric analysis of global research trends in adoptive cell therapy for triple negative breast cancer over the past 15 years. [PDF]

Discov Oncol
Elenien WIA, Ibrahim NA, Mohamed M, Elenien YA, Heiba M, Abouelenin O, Mahmood DA, Hussein FK.   +7 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Risk Trajectory and Right Ventricular Adaptation in Selexipag-Based Triple Therapy for Pulmonary Arterial Hypertension. [PDF]

Anatol J Cardiol
Mahida K, Jagtap SR.
europepmc   +1 more source

Social capital-triple helix co-evolution: Learning from an emerging example

, 2013
Relationships are important inputs for economic development, yet surprisingly there is little knowledge about how science-based industries emerge and evolve.
Karlson, Brian, Callagher, Lisa
core  

The role of triple evolution in the formation of LISA double white dwarfs

Galactic double white dwarfs will be prominent gravitational wave sources for the Laser Interferometer Space Antenna (LISA). While previous studies have primarily focused on formation scenarios in which binaries form and evolve in isolation, we present ...
Jakob Stegmann, Silvia Toonen, Stephen Justham, Abinaya Swaruba Rajamuthukumar, Valeriya Korol, Selma E. de Mink, Holly Preece, Rüdiger Pakmor   +7 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Impact of Early Diagnosis and Immunosuppressive Therapy on Giant Cell Myocarditis Outcomes: A Review. [PDF]

Life (Basel)
Kundnani NR, Kumar A, Sharma A, Mihai BVM, Diana Ardelean C, Marin-Bancila L, Valcovici M, Levai C, Iancu A, Rosca CI.   +9 more
europepmc   +1 more source