Results 71 to 80 of about 5,654,392 (381)

Epigenetic opportunities for Evolutionary Computation [PDF]

arXiv, 2021
Evolutionary Computation is a group of biologically inspired algorithms used to solve complex optimisation problems. It can be split into Evolutionary Algorithms, which take inspiration from genetic inheritance, and Swarm Intelligence algorithms, that take inspiration from cultural inheritance. However, recent developments have focused on computational
arxiv  

Stability of evolutionary algorithms

Journal of Mathematical Analysis and Applications, 2008
AbstractWe prove under mild conditions the convergence of some evolutionary algorithm to the solution of the global optimization problem. In the proof, the Lyapunov function's techniques is applied to some semi-dynamical system generated by a Foias operator on the space of the probability measures defined on the set of admissible solutions.
openaire   +3 more sources

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

An Analytic Expression of Relative Approximation Error for a Class of Evolutionary Algorithms [PDF]

, 2015
An important question in evolutionary computation is how good solutions evolutionary algorithms can produce. This paper aims to provide an analytic analysis of solution quality in terms of the relative approximation error, which is defined by the error between 1 and the approximation ratio of the solution found by an evolutionary algorithm.
arxiv   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Runtime Analysis of Competitive co-Evolutionary Algorithms for Maximin Optimisation of a Bilinear Function [PDF]

arXiv, 2022
Co-evolutionary algorithms have a wide range of applications, such as in hardware design, evolution of strategies for board games, and patching software bugs. However, these algorithms are poorly understood and applications are often limited by pathological behaviour, such as loss of gradient, relative over-generalisation, and mediocre objective stasis.
arxiv  

On the Analysis of Evolutionary Algorithms [PDF]

, 2001
There is a lot of experimental evidence that crossover is, for some functions, an essential operator of evolutionary algorithms. Nevertheless, it was an open problem to prove for some function that an evolutionary algorithm using crossover is essentially more efficient than evolutionary algorithms without crossover.
Jansen, Thomas, Wegener, Ingo
openaire   +2 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Metaheuristic Techniques in Enhancing the Efficiency and Performance of Thermo-Electric Cooling Devices

Energies, 2017
The objective of this paper is to focus on the technical issues of single-stage thermo-electric coolers (TECs) and two-stage TECs and then apply new methods in optimizing the dimensions of TECs. In detail, some metaheuristics—simulated annealing (SA) and
Pandian Vasant, Utku Kose, Junzo Watada
doaj   +1 more source