An alternative approach to medical genetics based on modern evolutionary biology. Part 2: retroviral symbiosis [PDF]
Frank Ryan
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An Aristotelian Account of Evolution and the Contemporary Philosophy of Biology [PDF]
The anti-reductionist character of the recent philosophy of biology and the dynamic development of the science of emergent properties prove that the time is ripe to reintroduce the thought of Aristotle, the first advocate of a “top-down” approach in life-
Tabaczek, Mariusz
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SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Frail hypotheses in evolutionary biology. [PDF]
Jacques Ninio
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Evolution of queen pheromone receptor tuning in four honeybee species (Hymenoptera, Apidae, Apis)
Summary: Honeybees (genus: Apis) use a plethora of pheromones for intraspecific communication. The primary compound produced by the queen’s mandibular glands, 9-ODA, is involved in mating in all Apis species. It is the ligand of the most highly expressed
Julia Mariette +10 more
doaj +1 more source
Interdisciplinary approaches to predicting evolutionary biology. [PDF]
Crocker J +3 more
europepmc +1 more source
It's time to get together: Announcing the new society for evolutionary developmental biology in the Americas [PDF]
Ehab Abouheif, Karen E. Sears
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Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Editorial: Aquatic genomics and transcriptomics for evolutionary biology. [PDF]
Ovchinnikova TV, Shi Q.
europepmc +1 more source

