Results 41 to 50 of about 67,250 (123)

The use of information theory in evolutionary biology [PDF]

open access: yesAnnals NY Acad. Sciences 1256 (2012) 49-65, 2011
Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a population adapts to a local environment, information about this environment is fixed in a representative genome. However,
arxiv   +1 more source

Cancer systems biology in the genome sequencing era: Part 2, evolutionary dynamics of tumor clonal networks and drug resistance [PDF]

open access: yes, 2014
A tumor often consists of multiple cell subpopulations (clones). Current chemo-treatments often target one clone of a tumor. Although the drug kills that clone, other clones overtake it and the tumor reoccurs. Genome sequencing and computational analysis allows to computational dissection of clones from tumors, while singe-cell genome sequencing ...
arxiv   +1 more source

Evolution of macromolecular structure: a 'double tale' of biological accretion [PDF]

open access: yesScience Progress 101(4):360-383, 2018, 2018
The evolution of structure in biology is driven by accretion and change. Accretion brings together disparate parts to form bigger wholes. Change provides opportunities for growth and innovation. Here we review patterns and processes that are responsible for a 'double tale' of evolutionary accretion at various levels of complexity, from proteins and ...
arxiv   +1 more source

Genome structure and evolutionary history of frankincense producing Boswellia sacra

open access: yesiScience, 2022
Summary: Boswellia sacra Flueck (family Burseraceae) tree is wounded to produce frankincense. We report its de novo assembled genome (667.8 Mb) comprising 18,564 high-confidence protein-encoding genes.
Abdul Latif Khan   +20 more
doaj  

Evolution of Generalists by Phenotypic Plasticity

open access: yesiScience, 2020
Summary: Adapting organisms face a tension between specializing their phenotypes for certain ecological tasks and developing generalist strategies that permit persistence in multiple environmental conditions.
David T. Fraebel   +3 more
doaj  

Evolutionary activation of acidic chitinase in herbivores through the H128R mutation in ruminant livestock

open access: yesiScience, 2023
Summary: Placental mammals' ancestors were insectivores, suggesting that modern mammals may have inherited the ability to digest insects. Acidic chitinase (Chia) is a crucial enzyme hydrolyzing significant component of insects' exoskeleton in many ...
Eri Tabata   +5 more
doaj  

Robust 3D modeling reveals spatiosyntenic properties of animal genomes

open access: yesiScience, 2023
Summary: Animal genomes are organized into chromosomes that are remarkably conserved in their gene content, forming distinct evolutionary units (synteny).
Tereza Clarence   +5 more
doaj  

Early genome erosion and internal phage-symbiont-host interaction in the endosymbionts of a cold-seep tubeworm

open access: yesiScience, 2023
Summary: Endosymbiosis with chemosynthetic Gammaproteobacteria is widely recognized as an adaptive mechanism of siboglinid tubeworms, yet evolution of these endosymbionts and their driving forces remain elusive.
Zhao-Ming Gao   +7 more
doaj  

Neutrality: A Necessity for Self-Adaptation [PDF]

open access: yesProceedings of the Congress on Evolutionary Computation (CEC 2002), 1354-1359., 2002
Self-adaptation is used in all main paradigms of evolutionary computation to increase efficiency. We claim that the basis of self-adaptation is the use of neutrality. In the absence of external control neutrality allows a variation of the search distribution without the risk of fitness loss.
arxiv  

Underlying Principles of Natural Selection in Network Evolution: Systems Biology Approach

open access: yesEvolutionary Bioinformatics, 2007
Systems biology is a rapidly expanding field that integrates diverse areas of science such as physics, engineering, computer science, mathematics, and biology toward the goal of elucidating the underlying principles of hierarchical metabolic and ...
Bor-Sen Chen, Wei-Sheng Wu
doaj  

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