Results 141 to 150 of about 46,925 (311)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Probability Selection-Based Surrogate-Assisted Evolutionary Algorithm for Expensive Optimization
Applied SciencesSurrogate-assisted evolutionary algorithms (SAEAs) have emerged as a powerful class of optimization methods that utilize surrogate models to address expensive optimization problems (EOPs), where fitness evaluations (FEs) are expensive or limited.
Siyuan Wang, Jian-Yu Li
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Evolutionary Robot Vision for People Tracking Based on Local Clustering
, 2008 This paper discusses the role of evolutionary computation in visual perception for partner robots. The search of evolutionary computation has many analogies with human visual search.
Sulistijono, Indra Adji, Kubota, Naoyuki
core
Use of evolutionary computation techniques for exploration and prediction of helicopter loads
, 2012 The development of accurate load spectra for helicopters is necessary for life cycle management and life extension efforts. This paper explores continued efforts to utilize evolutionary computation (EC) methods and machine learning techniques to estimate
Julio J. Valdes +5 more
core +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Evolutionary Computation Meets Stream Processing [PDF]
Evolutionary computation has a great potential of exploiting parallelization, a feature often underemphasized when describing evolutionary algorithms (EAs).
Medvet, Eric +3 more
core +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Adaptive Bi-Operator Evolution for Multitasking Optimization Problems
BiomimeticsThe field of evolutionary multitasking optimization (EMTO) has been a highly anticipated research topic in recent years. EMTO aims to utilize evolutionary algorithms to concurrently solve complex problems involving multiple tasks.
Changlong Wang, Zijia Wang, Zheng Kou
doaj +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source