Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
For many companies it is important to protect their physical and intellectual property in an e cient and economically viable man- ner. Thus, specialized security companies are delegated to guard private and public property.
Kloimüllner, Christian, Raidl, Günther
core
An evolutionary computation-based sensitive pattern hiding model under a multi-threshold constraint in healthcare. [PDF]
Sharma S, Sharma R, Kumar S, Min H.
europepmc +1 more source
Water demand modelling using evolutionary computation techniques: integrating water equity and justice for realization of the sustainable development goals. [PDF]
Oyebode O +3 more
europepmc +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Blockchain enhanced distributed denial of service detection in IoT using deep learning and evolutionary computation. [PDF]
Prasad VVSH +6 more
europepmc +1 more source
Evolutionary Computation for Parameter Extraction of Organic Thin-Film Transistors Using Newly Synthesized Liquid Crystalline Nickel Phthalocyanine. [PDF]
Jiménez-Tejada JA +7 more
europepmc +1 more source
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi +15 more
wiley +1 more source
An Approach to Pattern Recognition by Evolutionary Computation
Evolutionary Computation has been inspired by the natural phenomena of evolution. It provides a quite general heuristic, exploiting few basic concepts: reproduction of individuals, variation phenomena that affect the likelihood of survival of individuals,
Fontanella, Francesco
core
Multiomics with Evolutionary Computation to Identify Molecular and Module Biomarkers for Early Diagnosis and Treatment of Complex Disease. [PDF]
Cheng H, Liang M, Gao Y, Zhao W, Guo WF.
europepmc +1 more source

