Results 51 to 60 of about 6,048,895 (335)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Outsourcing of energetically costly amino acids at the origin of animals
Nature CommunicationsAnimals are generally capable of synthesizing eleven amino acids, while the remaining nine—often referred to as essential—must be acquired through diet.
Niko Kasalo +2 more
doaj +1 more source
Remote Sensing, 2021 Remote sensing streams continuous data feed from the satellite to ground station for data analysis. Often the data analytics involves analyzing data in real-time, such as emergency control, surveillance of military operations or scenarios that change ...
Shimin Hu +6 more
doaj +1 more source
Evolutionary computer simulations [PDF]
Physica A: Statistical Mechanics and its Applications, 2002 10 pages, plain TEX, no figures, STATPHYS ...
openaire +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Sensors, 2021 Electroencephalography (EEG) signal classification is a challenging task due to the low signal-to-noise ratio and the usual presence of artifacts from different sources.
Diego Aquino-Brítez +6 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Music and Evolutionary Computation
, 2011 This paper presents a brief history of the western music: from its genesis to serialism and the Darmstadt school. Also some mathematical aspects of music are then presented and confronted with music as a form of art. The question is, are these two distinct aspects compatible? Can computers be of real help in automatic composition?
Reis, Cecília +2 more
openaire +2 more sources
Theory of Evolutionary Computation [PDF]
Algorithmica, 2010 Evolutionary algorithms are general-purpose randomized search heuristics. They have been successfully applied to many different kinds of search and optimization problems. They are popular in practice since they are easy to implement and easy to apply, and yet often find good solutions in reasonable time.
Benjamin Doerr, Thomas Jansen 0001
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source