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EVOLUTIONARY DYNAMICS IN CARCINOGENESIS
Mathematical Models and Methods in Applied Sciences, 2005We have previously demonstrated intra- and extra-cellular factors that govern somatic evolution of the malignant phenotype can be modeled through evolutionary game theory, a mathematical approach that analyzes phenotypic adaptation to in-vivo environmental selection forces.
Gatenby, Robert A. +2 more
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Evolutionary dynamics on graphs
Nature, 2005Evolutionary dynamics have been traditionally studied in the context of homogeneous or spatially extended populations. Here we generalize population structure by arranging individuals on a graph. Each vertex represents an individual. The weighted edges denote reproductive rates which govern how often individuals place offspring into adjacent vertices ...
Erez, Lieberman +2 more
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The evolutionary dynamics of audit
European Journal of Operational Research, 2012zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nikolaos P. Anastasopoulos +1 more
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Unifying Evolutionary Dynamics
Journal of Theoretical Biology, 2002Darwinian evolution is based on three fundamental principles, reproduction, mutation and selection, which describe how populations change over time and how new forms evolve out of old ones. There are numerous mathematical descriptions of the resulting evolutionary dynamics.
Karen M, Page, Martin A, Nowak
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Dynamics of evolutionary robustness
Proceedings of the 8th annual conference on Genetic and evolutionary computation, 2006Recently there has been considerable interest in determining whether, and how much, evolutionary pressure for genetic robustness influences evolutionary processes. In this paper, we attempt to show that this evolutionary pressure does have a significant effect in typical genetic programming problems.
Alan Piszcz, Terence Soule
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Evolutionary Games and Local Dynamics [PDF]
In this paper, we examine several options for modeling local interactions within the framework of evolutionary game theory. Several examples show that there is a major difference between population dynamics using local dynamics versus global dynamics. Moreover, different modeling choices may lead to very diverse results.
Philippe Uyttendaele, Frank Thuijsman
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Replicator Dynamics of Evolutionary Hypergames
IEEE Transactions on Systems, Man, and Cybernetics - Part A: Systems and Humans, 2004In evolutionary game theory, the distribution of strategies in the population is changed according to payoffs which individuals earn depending on their selected strategies. However, to the best of our knowledge, individuals' perceptions in evolutionary games have been disregarded.
Takafumi Kanazawa +2 more
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The Evolutionary Dynamics of Bluetongue Virus
Journal of Molecular Evolution, 2010Bluetongue virus (BTV) is a midge-borne member of the genus Orbivirus that causes an eponymous debilitating livestock disease of great agricultural impact and which has expanded into Europe in recent decades. Reassortment among the ten segments comprising the double-stranded (ds) RNA genome of BTV has played an important role in generating the epidemic
Carpi, Giovanna +2 more
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Evolutionary dynamics of enzymes
"Protein Engineering, Design and Selection", 1995This paper codifies and rationalizes the large diversity in reaction rates and substrate specificity of enzymes in terms of a model which postulates that the kinetic properties of present-day enzymes are the consequence of the evolutionary force of mutation and selection acting on a class of primordial enzymes with poor catalytic activity and broad ...
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