Results 171 to 180 of about 4,260,217 (298)

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Decoding of amidated aromatic C-terminus and sulfation by cholecystokinin receptors reveals conserved and divergent evolutionary mechanisms. [PDF]

J Biol Chem
Chang JH, Wu SQ, Ding XY, Pan X, Wang HY, He YX, Xi L, Mei YS, Liu CY, Liu CP, Mao RT, Li F, Zhang YL, Li JY, Zhang G, Jing J.   +15 more
europepmc   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Implementation in adaptive better-response dynamics: Towards a general theory of bounded rationality in mechanisms. [PDF]

We study the classic implementation problem under the behavioral assumption that agents myopically adjust their actions in the direction of better-responses or bestresponses.
Serrano, Roberto, Cabrales, Antonio
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Desiccation Tolerance in Moss and Liverwort: Insights into the Evolutionary Mechanisms of Terrestrialization. [PDF]

Int J Mol Sci
Ghosh TK, Nazran A, Khan I, Naimul Islam SM, Islam T, Islam T, Xu Y, Mostofa MG.   +7 more
europepmc   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Hydrogeochemical Evolutionary Mechanisms and Irrigation Suitability of Phreatic Water in a Cherry Cultivation Zone of China. [PDF]

ACS Omega
Zhan H, Liu L, Fan Z, Feng Q, Cao Y, Yang F, Liu W, Cui S, Leng X, Liu B.   +9 more
europepmc   +1 more source

Historical genomics reveals the evolutionary mechanisms behind multiple outbreaks of the host-specific coffee wilt pathogen Fusarium xylarioides. [PDF]

BMC Genomics, 2021
Peck LD, Nowell RW, Flood J, Ryan MJ, Barraclough TG.   +4 more
europepmc   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

An evolutionary system for design exploration

, 2009
This paper reports on the development of a multi-objective evolutionary developmental design environment, called EDDE. The goal of the system is to make it easier for designers to use evolutionary techniques to explore design possibilities.
P. Janssen, Janssen, P.H.T.
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