Results 141 to 150 of about 888,235 (335)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Evoluzionismo e gestaltismo. La psicologia della forma e il problema della genesi

open access: yesAisthesis, 2013
This article carries out a critique of the abstract and disembodied character owned by the structures of the Psychology of Form. The Psychology of Form ignores and removes the genesis of forms, thus remaining trapped in the "dialectic of enlightenment ...
Michele Gardini
doaj  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Effect of Temperature on the Lattice Strain Evolution in a Textured Alpha Titanium: Neutron Diffraction and Modelling

open access: green, 2023
Kodjo Emmanuel Agbovi   +6 more
openalex   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Suramin Affects the Renal VEGF-A/VEGFR Axis in Short-Term Streptozotocin-Induced Diabetes. [PDF]

open access: yesPharmaceuticals (Basel), 2023
Chyła-Danił G   +8 more
europepmc   +1 more source

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